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Trials ; 21 1 :Mar Structured implementation of the associated patient version of the guideline maria bartholdi single missing to date.

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The study aims to assess whether structured implementation of a patient guideline improves the empowerment of patients with severe mental disorders, as well as knowledge, attitudes and experiences regarding psychosocial interventions, service use, treatment satisfaction, treatment needs, quality of life and burden of care.

METHODS: The study is a multicentre, cluster-randomised, controlled study with two parallel groups.

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Inpatients and day hospital patients all sexes; years with severe mental disorders will be included. In the experimental group, the patient guideline will be implemented using a multimodal strategy. Participants in the control group will receive treatment as usual but maria bartholdi single be made aware of the patient guideline.

JAMA Psychiatry ; 77 5 :05 Article En MEDLINE ID: mdl Importance: Identifying psychosis subgroups could improve clinical and research precision. Research has focused on symptom subgroups, but there is a need to consider a broader clinical spectrum, disentangle illness trajectories, and investigate genetic associations.

The primary outcome is the change of empowerment, assessed by using the 'empowerment in the process of psychiatric treatment of patients with affective and schizophrenia disorders' EPAS scale. In addition, knowledge, attitudes and experiences regarding psychosocial interventions will be assessed as secondary outcomes, as well as service use, satisfaction with care, patient need and quality of life and participation and social inclusion.

For relatives, the perceived burden of care also will be recorded. Results will be analysed using hierarchical linear models.

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For the health economic evaluation, the incremental cost-utility ratios will be computed using the differences in total costs of illness and the differences in quality-adjusted life years QALY between study groups.

The study has some limitations regarding the transferability of the results to other patients and other regions. Furthermore, problems with the recruitment of patients and relatives and with the implementation of intervention partnersuche walsrode occur during the study.

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